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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f853dbf6e962aa66519b27c56ecd32fa59c8dbc3da51b8d712af9f69c7aa515' 
  AND token = '3Mulz8l0dPO/+HsaZUT/kHIalNkl5Iy8p/kQpvKM+so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}