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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ffe388c04da6f768fa6ab6e88f4f128a883c82667e9254eef0f956d6780fea' 
  AND token = 'LuHSrtSzE3Arw8xfs0Tf+nosJ7GRydBq8/Yco6Zl/Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}