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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96676ae4339f005c0e2ea021984ea75776b71d23cd9888b8e9d0b46d20e2327d' 
  AND token = 'tO8e+hJ26W4MjtjNJ2y5uZKU0DFrA47vrPPlZblHN+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}