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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e1f8a3aab70fd5977c5945e82f2ee53d9c0f9180095cba90171ec3b4340234' 
  AND token = 'pBG4LT3WkEfLdc+NhsNkeQdLc+HTtLDSagVPLvSvKyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}