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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdd03f1c09abec993766e976c4e5f04e9cac863eed3dd7daa179df4a6cf0a6d0' 
  AND token = 'tv6vmdXMYUSCEcikGFiv6FNgdTqTLYWZC1xuwwAZ8S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}