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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dcc022b0d456f25e13de779d3a2a232a017ceec197f84cd248bf7d0f3a75012' 
  AND token = '8ysfrHFtcdoXUD+v6yr/zLxTAHRlxa9ICdBQBdB6zaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}