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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44244e699f630326f485b9aa1a82ddfb529f094e0b52ff48039122b8338a6a72' 
  AND token = 'kkm/7b4GTtgmNATQuXdq0W8Bz3Pl3QG0cSMtaMja3So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}