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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d9719b15e7d009f5dd8c3622ba6f9a4db2cdd4446c57718c0fe22d879819a29' 
  AND token = 'mVIWQyeougNt0nT1zEOi8pNCqd4/jpFN0t+uHX05FP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}