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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e41da4ff3c017209240e1ecfc3eee11a4de00eab0e080c79cf9531da4cabd8d' 
  AND token = '1gEc81jzFlBsFoy5CLFxc3FjD/06OXyhLo+SUbDdtcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}