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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a825db22a6ad051dd2072d7a37ee2d6245537d12654693e3b9d20b4e3d4b80de' 
  AND token = '14G4waBfaInS+7v4K2sAMZvVwKTFuFxNlRECv4CSrzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}