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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5027a3762af415faaef8a2cfc1056cdb31f1c13a8623f9ecfac4abd0b2c0d00b' 
  AND token = 'aFxk1g9Bu9pMHkAq5BRR28RP5wf8rFJbjvfJz3Q6jTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}