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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '699441df08dfed2a98cbfe1a7712ff189f657f7ee5fc23685424af1c61aa7089' 
  AND token = 'yR9B8mksGuMLxGPWe5L+pSk9hALxTMzwanm5frMzrYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}