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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2161804a39a72b54272bcf8f8c5e412b649e02455f4d190367414d561b176f6b' 
  AND token = 'xP9FmOBRmreGEb8DZ2IsI3mu43BJlyax81B/CzlETWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}