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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b80956a01f1e62f0f711b9a1583a95946dcbf0a2358c06a1c1aa242241c16d' 
  AND token = 'MT/7Lmb8NMFbANNRfx7T50BokVeod4vFH9cmW5m0O+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}