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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed2a9ae43dc4087798e03ef20b05a8a78eca695308d98d65c025559ef95f0bd' 
  AND token = '/29At/wK89B20x15SMMEx0h4G/INZqBpF1QknOYD7Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}