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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043a2453d488878da72f1f29e251d9ed2b135b983ef49d2b7e0ec35c9e2ea90a' 
  AND token = 'qQmIdsxdOocCT36jIzZUFbkSdrPIT4dn/UHXSp+ljW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}