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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e270709236bbe7c82c0c4402dad613cf3c27b29ad22fdfd1215a022ff6262a4' 
  AND token = 'WjC0ceVFXG5tgp8KjHAuFkCDEGz1Zuy2Nu/4KRM8SC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}