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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c9a202730a2fc5d4ddff518c5361ede655236ade45f2c2d63170920f7d8b4c' 
  AND token = 'ZdXXN/ST40PIi6Qqv0v2blrZEumxxL1Q8oml5HI/bx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}