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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e451a75709dd7020f3346390d360da6816b922dd51cb2aafe01f8e0f330ae170' 
  AND token = 'hk0MJmaFy3QXmhj6JYe2hdssFrT1MbWfkF2lcTLDJ54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}