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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37410aa06ddf6c81f9e4d1c9dde1225c24a1484167301a46b7d72c9602c85d44' 
  AND token = 'qmDgl026LJKOdRJN2Ke+oq59mWw3AFpRaOP2kKcY9SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}