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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a3b8da6f18d4c5d471bb4e52b059315cabce16ba306d2d7cc9d17e13e43b241' 
  AND token = 'j3j9HtzyAmqX/gVflYfrwaRhRA6KhOuBa7FEEUE9iiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}