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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f6a1335736fcf780305a944ee5a0ae24b1453a473ea862093747a37e428c7eb' 
  AND token = 'reA1R1vD22fnz5dyyjx+IMXwlIeNKWbTDJOXqEjCoek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}