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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e52afd677e4eddd023fb827d6b0b5b51bee188d508b4c313fb4552f7a17712b5' 
  AND token = 'GRGpWmgGN+i94Jd+lXpqM+37n6e2x/HIGq3bfI26HnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}