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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd772e5378b75f8070dfbf959d50fbd03b337ca73b8efdb5f6ecff2efff91d55a' 
  AND token = 'TTXIZ2IWUcpt+9P+CrYpIz57Y2v2HLR6vOxfXCcUCws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}