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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc0e86a5e71256b5206242cf7570182f3931d4c9276c4751fdbaec56b4181643' 
  AND token = 't9eLuoe2ykS6EvS+UHdNV7rPIKv547cA3BFZirJW6cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}