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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '267e708bfb8c31a49758ca9885cf65766cceb76fd5c2731a1af4195697fe33fb' 
  AND token = 'vk1ESGV7URrLkpoIXx91Aynxkl8Ni/98a2Rs4xj9Hfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}