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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8101a80a059e62377d791096293543bc9060b84f51efd3776a5b1b8294397047' 
  AND token = '1/7QLOv/pwWOxRXM75819qH/SZ6MJ6L1CaQLh4kYm48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}