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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0466ee4005e61a0ad89b018918287b5386bee5fbd6eefbb92559566356f1062' 
  AND token = 'Lh5U4eR+Sv1RfJ2s0s32Ta9DjdQPJHTHA090Q5x5obs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}