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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6263226b24c0e0a55da8c01316aaecc41e495b600467765c30267168921151a1' 
  AND token = 'vKgrleXsBUM9+i6y+zVdwPOg2hxSXMX9P5Z5bUg1O8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}