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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c3ba26bd3ed4235cf1da9a797db955d811c9387bffb83c53db79f7d9b47237e' 
  AND token = 'vHPnCt/NE+aHlN2ytJ+Rde2vg9/EO5QRs4lTth/svEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}