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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c55957e54edd2d7721b6e4bf52f4c2b55e21e043b3d98c33bbaa491cdb56ce1' 
  AND token = 'kDhBrORh0IxPtfi6I4/VVBGwD0WL216dqCrZV81IuLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}