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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b426ac73f6a26129d0ab7f35df11d0fcafa32656f62318891bc482815e508c7d' 
  AND token = 'z3hO/PkLP46yLI4zg1g5Cbr6sPPcZ49rk0oHm+T2LEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}