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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8a3fd266106097831086c4435af649d89884dfb611fb80e661fe763b27c866b' 
  AND token = 'da82btdF+UeucGrPlb3v1z82DQzSP9Pqf6/uLoMPfQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}