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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8943329b5341c94482397e153e9eed5c3f2341a3e337095b108b28e1f529b9d2' 
  AND token = 'Y4dA1HsNVBdwpbbTisswKbPwSdELh9zQxmhduP5OHjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}