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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d331734fafab88dbd39f3a15a0f6a342e0a3c21f1c5012ae68db31bf45c3b2' 
  AND token = 't9iQwxj9G3siSwYznynqJukSbcve9YUpRnZdI5x9jrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}