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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e2d2f0eae47a1dfe358cc1340c690534af5f9f5036e42b790e28f3718ecd6e' 
  AND token = 'Yq5BdD+S2kpv/OCcfcTr26BU7ALnyfeXcAOlbLQSyH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}