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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0051e4069ed00d562dbcce33a160d7534019b7933a457c4970dd3bca3a4c1ef2' 
  AND token = 'ZdwNYMDHIciMF9ski0nb8QVeyzyi+Ey8TtIhXO5SnGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}