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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e8c077380db07b7eae619bae2009c4fedac76fcbe36b05cd5ceead6a267530' 
  AND token = 'SL4j3P4e94stBgecjyt9vxmXiK+KBex8MtbCHwFo3Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}