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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb65ba5ba6d912e7fd6e706a39c7833882dff6616014e96bd4ae1bb5186337ee' 
  AND token = 'iizuDFO4ZK0UwMbzMI/RDxkacr3zLZCLPrA5IfobUgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}