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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd324940901712140446d9cc659124134cf8a258e3c7a9f1a02880a587508bf' 
  AND token = 'OepROCLEX5+C5nVuXcxtmx3g8UfeIk5r10jMiw085pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}