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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6f2e0e959a445851ac6e48afe47c48e63be53aea83129f1d1ce9ac9050dbf00' 
  AND token = 'TjLlPvK8pkPsp5h50g7YGOCvSoPJ9b92dM7s5LOFmN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}