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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cddb64d9269e3aa913e961d1d6481ea2a29b4c02157ff17ef543c619b2c2bd52' 
  AND token = 'pkfe9odj3v9DqRnO7FG0upAtp0m7ekihoZbnoTjjDhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}