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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd246202e85c34216264e4e9f6015de14dadc7bd08d23abfc970764287d1fee2' 
  AND token = 'OMUpklvA4Jyw8c94NWoSe/MnJRxXylXdMDSY4bZxsoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}