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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8506e30c8143df20ee0e0f3358d2d2e0337da0c46da89662d7d1a800f58623' 
  AND token = '/44324LGxSG6ig1Zo8HvujNzGKzGZXLwjDiYzpkziOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}