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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec0c301a15ff8a1d93ae1b9383bc7b673893dd31069de028e58662dedccb7ce9' 
  AND token = 'AZ16pqd20y2yTv0gDED6xYVeGwQQVLlo5EqZStUTpgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}