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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27991d1a234ee533281b7374b5d617d3e861a3ef082e69b773df0f1424683c2e' 
  AND token = 'lss5KfzqK0cfJgLeIEOxB6712azazId3OdI4AOGiyG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}