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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f21c59d77202867c233e9c9dbfeba791f4601b8662880f2c3a2502a41cea5667' 
  AND token = 'nP1L/ZHPHdP0Bx2FNCpIyCJFOn2Z8W7DHzC7UcnalD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}