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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6b26f582ec597c1354faaa9a518d877be1ea4ee4550adea9b547dc1e8fcd6b' 
  AND token = '9uCjiJDXU+wDu6k/LtmCrOruDqfOvD9M+DE1MRvPB9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}