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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a57a58ff0efe10cb4f740ae210c9656a735b4cc57c9a745488b6ffa1f1af9a6' 
  AND token = '8p2fUj1CMGBQjGsYpQyRTRVkboaTdEQfdn3qV73Ocms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}