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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9daaabac9fcbf9b042e6022e512b21bb2794ba2d20030b626d248e8253fd69d8' 
  AND token = 'FhQ3oRZM3odkbo4N66Ch30h56uhbh4EOMZEtweiThB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}